Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005330 | 0.87 | TLR8 (0.51) | TLR8SMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL741255 | 0.84 | KDM4E (0.61) | TLR8SMN1; SMN2KDM4ELMNATP53 | |
| SCHEMBL7004498 | 0.84 | TLR8 (0.52) | TLR8SMN1; SMN2KDM4ELMNARAB9A | |
| SCHEMBL7004330 | 0.80 | ALDH1A1 (0.54) | TLR8SMN1; SMN2KDM4ELMNARAB9A | |
| SCHEMBL15361972 | 0.79 | TLR8 (0.54) | TLR8SMN1; SMN2KDM4ELMNARAB9A | |
| SCHEMBL7007754 | 0.77 | NPC1 (0.54) | TLR8SMN1; SMN2KDM4ELMNATP53 | |
| SCHEMBL7003762 | 0.76 | TLR8 (0.49) | TLR8SMN1; SMN2KDM4ELMNARAB9A | |
| SCHEMBL28653821 | 0.75 | TLR8 (0.60) | TLR8SMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL7003760 | 0.73 | S1PR1 (0.48) | TLR8SMN1; SMN2KDM4ELMNATP53 | |
| SCHEMBL7004489 | 0.72 | PDE10A (0.52) | TLR8SMN1; SMN2KDM4ETP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |