Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007443 | 0.90 | MEN1 (0.51) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL7006729 | 0.79 | ALOX5 (0.48) | L3MBTL1ALOX5MAOBMAOAMEN1 | |
| SCHEMBL7009665 | 0.78 | ALOX5 (0.47) | L3MBTL1ALOX5MAOBMAOAMEN1 | |
| SCHEMBL7006801 | 0.78 | MAPK14 (0.54) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL7004499 | 0.76 | MCHR1 (0.47) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL7004603 | 0.75 | ALDH1A1 (0.40) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL7002364 | 0.74 | NPC1 (0.47) | L3MBTL1MEN1NPC1KMT2ARAB9A | |
| SCHEMBL7003158 | 0.73 | MAPK14 (0.48) | ALOX5CHEK1MAPK14CYP3A4 | |
| SCHEMBL7001976 | 0.73 | MCHR1 (0.47) | ALOX5MAOBMEN1NPC1KMT2A | |
| SCHEMBL7005823 | 0.73 | ALOX5 (0.41) | NSD2ABL1PPARGRIN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |