Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 14/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009665 | 0.92 | ALOX5 (0.47) | NPC1RAB9AL3MBTL1MCHR1GRM5 | |
| SCHEMBL7006729 | 0.82 | ALOX5 (0.48) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL7005823 | 0.80 | ALOX5 (0.41) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL7006801 | 0.79 | MAPK14 (0.54) | NPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL7004499 | 0.77 | MCHR1 (0.47) | NPC1RAB9AL3MBTL1MCHR1MEN1 | |
| SCHEMBL7001976 | 0.76 | MCHR1 (0.47) | NPC1RAB9AMCHR1MEN1KMT2A | |
| SCHEMBL7004088 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2A | |
| SCHEMBL7008033 | 0.75 | AS3MT (0.41) | — | |
| SCHEMBL7008773 | 0.75 | AS3MT (0.41) | NPC1MEN1KMT2A | |
| SCHEMBL7003213 | 0.74 | NSD2 (0.50) | NPC1RAB9AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |