Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 15/20 | 0.61 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | PRKACG | P22612 | 1/20 | 0.49 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7012664 | 0.94 | CAMK2D (0.56) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| SCHEMBL7007889 | 0.82 | CAMK2D (0.62) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| SCHEMBL7005430 | 0.82 | CAMK2D (0.59) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| SCHEMBL6980073 | 0.82 | CAMK2D (0.56) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| SCHEMBL7005339 | 0.81 | CAMK2D (0.55) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| Acetic Acid SCHEMBL7007558 | 0.78 | CAMK2D (0.53) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| Acetic Acid SCHEMBL6983601 | 0.78 | CAMK2D (0.52) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| SCHEMBL7007161 | 0.77 | CAMK2D (0.57) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| SCHEMBL7007656 | 0.76 | CAMK2D (0.57) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB | |
| Trifluoroacetic Acid SCHEMBL7011017 | 0.75 | CAMK2D (0.54) | CAMK2DRPS6KB1PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042317-B1 | Indole derivatives as PKC-inhiboitors | ASTRAZENECA AB (SE) | 2003-05-14 | — | — | EP | claimed |
| EP-1042317-B1 | Indole derivatives as PKC-inhiboitors | ASTRAZENECA AB (SE) | 2003-05-14 | — | — | EP | disclosed |