Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 15/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | PRKACG | P22612 | 1/20 | 0.50 |
| ▸ | PRKACB | P22694 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7013299 | 0.95 | CAMK2D (0.53) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL7671215 | 0.80 | CAMK2D (0.49) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL7007889 | 0.79 | CAMK2D (0.62) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL7005430 | 0.79 | CAMK2D (0.59) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL7004584 | 0.76 | CAMK2D (0.61) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL6983727 | 0.75 | CAMK2D (0.44) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| Acetic Acid SCHEMBL7012664 | 0.74 | CAMK2D (0.56) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL7009849 | 0.74 | CAMK2D (0.51) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL7011017 | 0.74 | CAMK2D (0.54) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL7007161 | 0.74 | CAMK2D (0.57) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042317-B1 | Indole derivatives as PKC-inhiboitors | ASTRAZENECA AB (SE) | 2003-05-14 | — | — | EP | claimed |
| US-6337342-B1 | ARYLIMIDAZOLONE DERIVATIVES | ASTRAZENECA AB (SE) | 2002-01-08 | — | — | US | claimed |
| EP-1042317-B1 | Indole derivatives as PKC-inhiboitors | ASTRAZENECA AB (SE) | 2003-05-14 | — | — | EP | disclosed |