Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12109510 | 0.83 | KDM4E (0.46) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL1202057 | 0.82 | ALDH1A1 (0.47) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL31391099 | 0.82 | KDM4E (0.48) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL18757922 | 0.81 | ALDH1A1 (0.46) | KDM4EKDM5AMAPTTDP1PIM1 | |
| SCHEMBL7721019 | 0.79 | DDAH1 (0.44) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL14336654 | 0.79 | KDM4E (0.43) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL697780 | 0.78 | KDM4E (0.54) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL7002080 | 0.78 | KDM4E (0.48) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL5271758 | 0.77 | KDM4E (0.44) | KDM4EKMT2AATMGAAPKN1 | |
| SCHEMBL937977 | 0.77 | PKM (0.48) | KDM4EKMT2AATMGAAPKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108645832-B | SERS chip and preparation method and application thereof | 苏州英菲尼纳米科技有限公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-108645832-A | A kind of SERS chips and its preparation method and application | 苏州天际创新纳米技术有限公司 | 2018-10-12 | — | — | CN | disclosed |
| WO-2003106430-A1 | BENZIMIDAZOLE INHIBITORS OF POLY(ADP-RIBOSYL) POLYMERASE | PFIZER INC. (US) | 2003-12-24 | — | — | WO | disclosed |