Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721019 | 0.87 | DDAH1 (0.44) | KDM4EKMT2AGAAATMMAPT | |
| SCHEMBL7145208 | 0.85 | BCHE (0.38) | KDM4EKMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL937977 | 0.85 | PKM (0.48) | KDM4EKMT2AGAAATMMAPT | |
| SCHEMBL1917771 | 0.85 | RIPK1 (0.44) | KDM4EKMT2AGAAATMMAPT | |
| SCHEMBL1552358 | 0.83 | RNASEH1 (0.54) | KDM4EKMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL3520029 | 0.83 | KDM4E (0.45) | KDM4EKMT2AGAAATMMAPT | |
| SCHEMBL9197306 | 0.83 | RIPK1 (0.48) | KDM4EKMT2AGAAATMMAPT | |
| SCHEMBL29261995 | 0.83 | CHRM1 (0.53) | KDM4EKMT2AGAAATMMAPT | |
| SCHEMBL20594099 | 0.83 | MAPT (0.46) | KDM4EKMT2AGAAATMMAPT | |
| SCHEMBL29894060 | 0.83 | CHRM1 (0.53) | KDM4EKMT2AGAAATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570683-B | Polysubstituted aminated compounds and its preparation method and application | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |
| WO-2003106430-A1 | BENZIMIDAZOLE INHIBITORS OF POLY(ADP-RIBOSYL) POLYMERASE | PFIZER INC. (US) | 2003-12-24 | — | — | WO | disclosed |