Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006045 | 1.00 | CASP6 (0.55) | CASP6TSHRHCAR3ALDH1A1MAPT | |
| SCHEMBL7006042 | 1.00 | CASP6 (0.55) | CASP6TSHRHCAR3ALDH1A1MAPT | |
| SCHEMBL192101 | 0.89 | HCAR3 (0.58) | CASP6TSHRHCAR3ALDH1A1MAPT | |
| SCHEMBL3091095 | 0.89 | HCAR3 (0.58) | CASP6TSHRHCAR3ALDH1A1MAPT | |
| SCHEMBL13778767 | 0.89 | MAPT (0.48) | CASP6TSHRHCAR3ALDH1A1MAPT | |
| SCHEMBL4133735 | 0.85 | VCAM1 (0.50) | ALDH1A1MAPTLMNABACE1 | |
| SCHEMBL3970653 | 0.85 | VCAM1 (0.50) | ALDH1A1MAPTLMNABACE1 | |
| SCHEMBL18653999 | 0.84 | CASP6 (0.60) | CASP6TSHRHCAR3LMNABACE1 | |
| SCHEMBL27634500 | 0.82 | HCAR3 (0.48) | CASP6TSHRHCAR3ALDH1A1MAPT | |
| SCHEMBL11833581 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322638-A1 | ANTIFUNGAL AND/OR ANTIPARASITIC PHARMACEUTICAL COMPOSITION AND NOVEL INDOLE DERIVATIVES AS ACTIVE PRINCIPLE OF SUCH A COMPOSITION | Yang Ji Chemical Company Ltd. (KR) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024685-A1 | INDOLE DERIVATIVES AND THEIR USE AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS | YANG JI CHEMICAL COMPANY LTD. (KR) | 2002-03-28 | — | — | WO | disclosed |