Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.53 |
| ▸ | NOS3 | P29474 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 2/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010984 | 1.00 | SLC6A4 (0.53) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL6965518 | 0.84 | SLC6A4 (0.65) | SLC6A4 | |
| SCHEMBL6965512 | 0.81 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL6997941 | 0.81 | SLC6A4 (0.41) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL7006323 | 0.79 | CYP1A2 (0.55) | NOS3NOS1NOS2 | |
| SCHEMBL7006768 | 0.77 | HTR6 (0.40) | — | |
| SCHEMBL7002561 | 0.76 | SLC6A4 (0.36) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL6997685 | 0.76 | SLC6A4 (0.36) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL7007800 | 0.76 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL7007803 | 0.76 | SLC6A4 (0.59) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | claimed |
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | disclosed |