Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.38 |
| ▸ | CTSG | P08311 | 3/20 | 0.38 |
| ▸ | CMA1 | P23946 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006251 | 0.94 | LTA4H (0.39) | LTA4HALOX5FAAHS1PR1CYP4Z1 | |
| SCHEMBL7013170 | 0.90 | FFAR1 (0.45) | FFAR1FAAHS1PR1CYSLTR2CYSLTR1 | |
| SCHEMBL2293422 | 0.84 | CTSG (0.37) | CTSGCMA1S1PR1 | |
| SCHEMBL2293418 | 0.84 | CTSG (0.37) | CTSGCMA1S1PR1 | |
| SCHEMBL4510764 | 0.84 | FFAR1 (0.43) | FFAR1FAAHS1PR1CYSLTR2CYSLTR1 | |
| SCHEMBL4510771 | 0.84 | FFAR1 (0.43) | FFAR1FAAHS1PR1CYSLTR2CYSLTR1 | |
| SCHEMBL4602072 | 0.84 | GAA (0.37) | LTA4HCTSGCMA1CYP4Z1 | |
| SCHEMBL2291756 | 0.84 | GAA (0.37) | LTA4HCTSGCMA1CYP4Z1 | |
| SCHEMBL2291750 | 0.84 | GAA (0.37) | LTA4HCTSGCMA1CYP4Z1 | |
| SCHEMBL8240110 | 0.84 | RAB9A (0.42) | CTSGCMA1ALOX5FFAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183271-B2 | Tetrazole derivatives and their use for the treatment of cardiovascular diseases | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-05-22 | — | — | US | disclosed |
| US-20090215843-A1 | Tetrazole Derivatives and Their Use for the Treatment of Cardiovascular Diseases | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215843-A1 | Tetrazole Derivatives and Their Use for the Treatment of Cardiovascular Diseases | TNNI3, TNNT2, FABP3 | LTA4H 1798/4885CTSG 1721/4885CMA1 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.