Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | CES2 | O00748 | 3/20 | 0.67 |
| ▸ | CES1 | P23141 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29116440 | 0.85 | LMNA (0.66) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL6836823 | 0.84 | LMNA (0.69) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL29262742 | 0.83 | LMNA (0.67) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL812736 | 0.83 | LMNA (0.67) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL10794860 | 0.81 | LMNA (0.65) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL901258 | 0.81 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL5833429 | 0.81 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL2025536 | 0.81 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL145 | 0.81 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL10665271 | 0.81 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032568-A4 | PROCESS FOR THE PREPARATION OF ISOFLAVONES | UNIV MICHIGAN STATE (US) | 2003-03-05 | — | — | EP | claimed |
| EP-1032568-A1 | PROCESS FOR THE PREPARATION OF ISOFLAVONES | MICHIGAN STATE UNIVERSITY (US) | 2000-09-06 | — | — | EP | claimed |
| WO-2000015627-A1 | PROCESS FOR THE PREPARATION OF ISOFLAVONES | MICHIGAN STATE UNIVERSITY (US) | 2000-03-23 | — | — | WO | claimed |