Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 8/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | HTR1D | P28221 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27534728 | 0.99 | MTNR1A (0.46) | MTNR1AMTNR1BHTR2CHTR2AHTR1A | |
| SCHEMBL7009759 | 0.82 | MTNR1B (0.45) | MTNR1AMTNR1BHTR2CHTR2AHTR1A | |
| SCHEMBL7228199 | 0.82 | MTNR1B (0.45) | MTNR1AMTNR1BHTR2CHTR2AHTR1A | |
| SCHEMBL7237660 | 0.78 | MTNR1B (0.42) | MTNR1AMTNR1BHTR2CHTR2AHTR1A | |
| SCHEMBL7237659 | 0.78 | MTNR1B (0.42) | MTNR1AMTNR1BHTR2CHTR2AHTR1A | |
| SCHEMBL7016214 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1BHTR2CHTR2AHTR1A | |
| SCHEMBL7012297 | 0.72 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL7012295 | 0.72 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL7357302 | 0.72 | MTNR1A (0.55) | MTNR1AMTNR1BHTR2CHTR2AHTR1A | |
| Ammonia Solution, Strong SCHEMBL27497763 | 0.72 | MTNR1A (0.46) | MTNR1AMTNR1BHTR2CHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |