Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RIPK3 | Q9Y572 | 10/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008536 | 0.86 | RIPK3 (0.45) | KMT2ARIPK3MAPK14 | |
| SCHEMBL7012237 | 0.86 | RIPK3 (0.45) | KMT2ARIPK3MAPK14 | |
| SCHEMBL6053689 | 0.84 | KMT2A (0.63) | KMT2AKDM4E | |
| SCHEMBL6294484 | 0.83 | KMT2A (0.69) | KMT2ARIPK3MAPK14KDM4E | |
| SCHEMBL7006189 | 0.83 | RIPK3 (0.44) | KMT2ARIPK3MAPK14 | |
| SCHEMBL7006701 | 0.81 | ALOX5 (0.41) | KMT2AKDM4E | |
| SCHEMBL7009622 | 0.79 | MAPK14 (0.48) | RIPK3MAPK14KDM4E | |
| SCHEMBL7001656 | 0.79 | KMT2A (0.52) | KMT2AKDM4E | |
| SCHEMBL6291337 | 0.77 | KMT2A (0.47) | KMT2ARIPK3MAPK14 | |
| SCHEMBL7009927 | 0.77 | KMT2A (0.47) | KMT2ARIPK3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252163-B1 | 4-PYRIDYL-AND 2,4-PYRIMIDINYL-SUBSTITUTED PYRROLE DERIVATIVES AND THEIR USE IN PHARMACY | MERCKLE GMBH (DE) | 2003-09-24 | — | — | EP | disclosed |