Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008036 | 0.82 | HPGD (0.62) | KMT2AMEN1HPGDMGLLTDP1 | |
| SCHEMBL1149992 | 0.80 | HPGD (0.65) | KMT2AMEN1HPGDCA12CA1 | |
| SCHEMBL21827037 | 0.77 | KMT2A (0.41) | KMT2AMEN1HPGDCA12CA1 | |
| SCHEMBL26102654 | 0.77 | HPGD (0.51) | KMT2AMEN1HPGDMGLLALDH1A1 | |
| SCHEMBL30143562 | 0.75 | HTR7 (0.39) | KMT2AMEN1TDP1GAACASP3 | |
| SCHEMBL21733177 | 0.73 | SIGMAR1 (0.35) | KMT2AMEN1HPGDNOTUM | |
| SCHEMBL27520534 | 0.72 | HPGD (0.36) | HPGDALDH1A1GAA | |
| SCHEMBL30143569 | 0.70 | MEN1 (0.38) | KMT2AMEN1HPGDCA12CA1 | |
| SCHEMBL11032644 | 0.70 | HPGD (0.59) | KMT2AMEN1HPGDMGLLTDP1 | |
| SCHEMBL2345232 | 0.70 | HPGD (0.68) | KMT2AMEN1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703798-A | Azaindolinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |