Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655114 | 0.81 | KMT2A (0.42) | KMT2AKIF11KCNH2HSD11B1HTT | |
| SCHEMBL7010039 | 0.80 | KMT2A (0.44) | KMT2AKIF11KCNH2HSD11B1HTT | |
| SCHEMBL28346610 | 0.76 | KIF11 (0.44) | KMT2AKIF11KCNH2ALDH1A1 | |
| SCHEMBL17173364 | 0.76 | CA4 (0.46) | KMT2AKIF11KCNH2ALDH1A1 | |
| SCHEMBL21562153 | 0.76 | CA4 (0.46) | KMT2AKIF11KCNH2ALDH1A1 | |
| SCHEMBL10495868 | 0.75 | KIF11 (0.45) | KMT2AKIF11KCNH2HSD11B1KDM4E | |
| SCHEMBL8388886 | 0.73 | SLC6A11 (0.44) | KMT2AKIF11KCNH2HSD11B1CYP3A4 | |
| SCHEMBL8454432 | 0.73 | KIF11 (0.45) | KMT2AKIF11KCNH2 | |
| SCHEMBL3996218 | 0.71 | KIF11 (0.49) | KIF11KCNH2 | |
| SCHEMBL9306492 | 0.71 | SLC6A11 (0.45) | KMT2AKIF11HSD11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816368-B1 | Chemical phoshorylation of oligonucleotides and reactants used therefor | GLEN RES CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-0816368-A1 | Chemical phoshorylation of oligonucleotides and reactants used therefor | Glen Research Corporation (US) | 1998-01-07 | — | — | EP | disclosed |