SCHEMBL700816

SCHEMBL700816

Cc1cccc(C)c1C(=O)NC1CCCCC1C

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 17/20 0.73
TAS1R1 Q7RTX1 16/20 0.73
TAS1R2 Q8TE23 16/20 0.73
MLYCD O95822 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703197 0.84 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2
SCHEMBL704631 0.84 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL701795 0.83 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL5270815 0.83 TAS1R3 (0.81) TAS1R3TAS1R1TAS1R2
SCHEMBL4176567 0.83 TAS1R3 (0.79) TAS1R3TAS1R1TAS1R2
SCHEMBL702131 0.83 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2
SCHEMBL13638984 0.83 TAS1R3 (0.79) TAS1R3TAS1R1TAS1R2
SCHEMBL700898 0.81 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2
SCHEMBL27916621 0.81 TAS1R3 (0.49) TAS1R3TAS1R1TAS1R2
SCHEMBL4177762 0.80 TAS1R3 (0.67) TAS1R3TAS1R1TAS1R2MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431464-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2019-01-23 EP claimed
US-10060909-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX, INC. (US) 2018-08-28 US claimed
CN-103275058-B Seasonings, taste modulators, tastant, taste enhancer, tasty agents or sweeting agent and/or toughener and uses thereof SENOMYX INC. (US) 2016-02-24 CN claimed
US-20150093339-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF FIRMENICH INCORPORATED 2015-04-02 US claimed
US-8709521-B2 Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles THE COCA-COLA COMPANY (US) 2014-04-29 US claimed
CN-101742924-B Sweetener compositions with enhanced sweetness and improved temporal and/or flavor profile COCA COLA CO 2014-01-29 CN claimed
CN-103275058-A Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC 2013-09-04 CN claimed
CN-102919807-A Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles COCA COLA CO 2013-02-13 CN claimed
US-20120201763-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX, INC. (US) 2012-08-09 US claimed
CN-101742924-A Sweetener compositions with enhanced sweetness and improved temporal and/or flavor profile COCA COLA CO 2010-06-16 CN claimed
EP-2160103-A1 SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES THE COCA-COLA COMPANY (US) 2010-03-10 EP claimed
CN-101400336-A Novel flavoring agents, taste modifiers, tastants, taste enhancers, umami or sweeteners and/or enhancers and uses thereof SENOMYX INC (US) 2009-04-01 CN claimed
US-20090053378-A1 Sweetener Compositions Having Enhanced Sweetness and Improved Temporal and/or Flavor Profiles THE COCA-COLA COMPANY (US) 2009-02-26 US claimed
WO-2008147726-A1 SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES THE COCA-COLA COMPANY (US) 2008-12-04 WO claimed
EP-1659881-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2006-05-31 EP claimed
WO-2005041684-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC. (US) 2005-05-12 WO claimed
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products FIRMENICH INCORPORATED 2005-04-21 US claimed
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 US disclosed
WO-2005041684-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC. (US) 2005-05-12 WO disclosed
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products FIRMENICH INCORPORATED 2005-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10060909-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof TAS1R2, TAS1R1, TAS2R40 TAS1R3 5/4885TAS1R1 2/4885TAS1R2 1/4885
US-20150093339-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R30 TAS1R3 5/4885TAS1R1 2/4885TAS1R2 1/4885
US-20120201763-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R30 TAS1R3 5/4885TAS1R1 2/4885TAS1R2 1/4885
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products TAS2R40, TAS2R4, TAS2R30 TAS1R3 17/4885TAS1R1 11/4885TAS1R2 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.