Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007153 | 0.94 | CHRNA7 (0.61) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL7015509 | 0.92 | CHRNA7 (0.59) | CHRNA7 | |
| Iodide SCHEMBL8219528 | 0.92 | CHRNA7 (0.59) | CHRNA7 | |
| SCHEMBL7510798 | 0.89 | CHRNA7 (0.55) | CHRNA7 | |
| SCHEMBL6406991 | 0.86 | MTNR1B (0.47) | CHRNA7 | |
| SCHEMBL521174 | 0.84 | CNR1 (0.48) | CHRNA7BRD4ATAD2 | |
| SCHEMBL7010627 | 0.75 | PDE7A (0.47) | CHRNA7 | |
| Iodide SCHEMBL7847003 | 0.75 | CHRNA7 (0.83) | CHRNA7 | |
| SCHEMBL22993435 | 0.74 | CHRNA7 (0.61) | CHRNA7 | |
| SCHEMBL8219167 | 0.74 | CHRNA7 (0.61) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102769-B1 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | disclosed |