Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7011688 | 0.99 | PDE7A (0.46) | PDE7APDE7BCHRNA7HSP90AA1HIF1A | |
| SCHEMBL7008003 | 0.94 | CHRNA7 (0.54) | PDE7APDE7BCHRNA7HTR1ADRD1 | |
| Hydrochloric Acid SCHEMBL7505359 | 0.93 | CHRNA7 (0.52) | PDE7APDE7BCHRNA7HTR1ADRD1 | |
| Iodide SCHEMBL8217289 | 0.93 | CHRNA7 (0.52) | PDE7APDE7BCHRNA7HTR1ADRD1 | |
| SCHEMBL7011686 | 0.78 | SLC18A3 (0.44) | HSP90AA1HIF1AHTR1A | |
| Nitric Acid SCHEMBL7014441 | 0.76 | CHRNA7 (0.68) | CHRNA7HTR1A | |
| SCHEMBL9495772 | 0.76 | SLC18A3 (0.46) | HSP90AA1HIF1AHTR1A | |
| SCHEMBL8216078 | 0.75 | MEN1 (0.60) | — | |
| SCHEMBL24740685 | 0.75 | PNMT (0.45) | — | |
| SCHEMBL7008801 | 0.75 | CHRNA7 (0.53) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102769-B1 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | disclosed |