Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3804684 | 0.88 | PPARG (0.54) | AGTR1PPARG | |
| SCHEMBL2844345 | 0.87 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL7011057 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL844779 | 0.84 | AGTR2 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL7015930 | 0.78 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL2132264 | 0.78 | AGTR2 (0.63) | AGTR1AGTR2 | |
| SCHEMBL684047 | 0.75 | PPARG (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL12857056 | 0.74 | — | — | |
| SCHEMBL7015932 | 0.74 | ABCB11 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL7016811 | 0.73 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520423-B1 | Heterocyclic compounds, their production and use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-14 | — | — | EP | claimed |