Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 18/20 | 0.63 |
| ▸ | CDK1 | P06493 | 18/20 | 0.63 |
| ▸ | CCNB1 | P14635 | 18/20 | 0.63 |
| ▸ | CCNB3 | Q8WWL7 | 18/20 | 0.63 |
| ▸ | GSK3B | P49841 | 16/20 | 0.63 |
| ▸ | GSK3A | P49840 | 14/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.63 |
| ▸ | CDK5R1 | Q15078 | 11/20 | 0.63 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101502 | 0.86 | CCNB2 (0.44) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL7016833 | 0.83 | CCNB2 (0.42) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1780850 | 0.81 | CCNB2 (0.71) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL7014990 | 0.81 | RIPK1 (0.48) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL5945897 | 0.79 | ERN1 (0.49) | — | |
| SCHEMBL7017680 | 0.78 | RIPK1 (0.43) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL7101268 | 0.78 | RIPK1 (0.43) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL491000 | 0.78 | GSK3B (1.00) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL29913107 | 0.78 | GSK3B (1.00) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL7100815 | 0.78 | RIPK1 (0.42) | CCNB2CDK1CCNB1CCNB3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294718-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096336-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |