Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ADH5 | P11766 | 1/20 | 0.56 |
| ▸ | PORCN | Q9H237 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005980 | 0.95 | CYP3A4 (0.69) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL10512975 | 0.88 | LMNA (0.62) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL6660795 | 0.86 | MEN1 (1.00) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| Water SCHEMBL6337291 | 0.84 | MEN1 (0.96) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL2533488 | 0.82 | TSHR (0.84) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL7658197 | 0.81 | ALOX15 (0.53) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL7650969 | 0.81 | ALOX15 (0.53) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL10126954 | 0.80 | LMNA (0.79) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL2364827 | 0.79 | MAOA (0.80) | MEN1ALOX15TSHRKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7650974 | 0.79 | ADH5 (0.51) | MEN1ALOX15TSHRKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065209-B1 | Metalloprotease inhibitors, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-05-02 | — | — | EP | disclosed |
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |
| EP-1065209-A1 | Metalloprotease inhibitors, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-01-03 | — | — | EP | disclosed |