Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013305 | 0.81 | HTR6 (0.39) | HTR6 | |
| SCHEMBL7010382 | 0.81 | HTR6 (0.39) | HTR6 | |
| SCHEMBL7006184 | 0.76 | SLC6A4 (0.36) | HTR6 | |
| SCHEMBL7005001 | 0.63 | HTR1A (0.47) | HTR6 | |
| SCHEMBL7006270 | 0.61 | HTR1B (0.58) | HTR6 | |
| SCHEMBL7006286 | 0.61 | HTR1B (0.58) | HTR6 | |
| SCHEMBL6969556 | 0.60 | SLC6A4 (0.61) | HTR6 | |
| SCHEMBL6966131 | 0.60 | SLC6A4 (0.58) | HTR6 | |
| SCHEMBL6426403 | 0.60 | HTR6 (0.48) | HTR6 | |
| SCHEMBL6740915 | 0.60 | HTR6 (0.48) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | disclosed |
| US-6329390-B1 | BIHETEROCYCLIC INDOLES AS ANALGESICS AND NERVOUS SYSTEM DISORDERS | NPS ALLELIX CORP. (CA) | 2001-12-11 | — | — | US | disclosed |
| EP-1098896-A1 | 5-BICYCLOINDOLE COMPOUNDS | NPS Allelix Corp. (CA) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004019-A1 | 5-BICYCLOINDOLE COMPOUNDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-01-27 | — | — | WO | disclosed |