Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669796 | 0.73 | MTNR1A (0.63) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7230327 | 0.70 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL7010965 | 0.70 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL8883217 | 0.68 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL6253217 | 0.68 | MAPT (0.44) | — | |
| SCHEMBL7013039 | 0.68 | MTNR1A (0.53) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7741714 | 0.68 | MTNR1A (0.47) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8671940 | 0.67 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL28723348 | 0.65 | MTNR1A (0.62) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7228835 | 0.64 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |