Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637953 | 0.72 | MTNR1A (0.60) | MTNR1AMTNR1BHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11718070 | 0.71 | KDM4E (0.53) | MTNR1AMTNR1BHSD17B10ALDH1A1HPGD | |
| SCHEMBL7741711 | 0.71 | MTNR1A (0.59) | MTNR1AMTNR1BAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10835932 | 0.69 | GAA (0.41) | ALDH1A1 | |
| SCHEMBL2689604 | 0.69 | FFAR1 (0.47) | — | |
| SCHEMBL8020435 | 0.69 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL29593962 | 0.69 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL6633664 | 0.68 | MTNR1A (0.62) | MTNR1AMTNR1BHTR2CHSD17B10ALDH1A1 | |
| SCHEMBL7741227 | 0.68 | MTNR1A (0.47) | MTNR1AMTNR1BHSD17B10AKR1C3AKR1C2 | |
| SCHEMBL27330863 | 0.68 | MTNR1A (0.54) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |