Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GPR174 | Q9BXC1 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012598 | 0.89 | GPR174 (0.59) | FFAR3KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7817859 | 0.83 | ALDH1A1 (0.63) | FFAR3KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL15450498 | 0.77 | GPR174 (0.74) | MAPTMEN1KMT2AGPR174TDP1 | |
| SCHEMBL7010448 | 0.76 | KDM4E (0.56) | FFAR3KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL18025754 | 0.74 | PDE4A (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7817258 | 0.74 | GPR174 (0.72) | FFAR3ALDH1A1MAPTGAAMEN1 | |
| SCHEMBL8876634 | 0.70 | ALDH1A1 (0.58) | FFAR3KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7820668 | 0.70 | ABCC9 (0.66) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL16211041 | 0.70 | SMN1; SMN2 (0.73) | FFAR3KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29538575 | 0.70 | GAA (0.61) | KDM4EALDH1A1HSD17B10ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103554-B9 | Derivatives of dihydrofuro-(3,4-b)-quinolein-1-ones, process of préparation and phamaceutical compositions containing them | SERVIER LAB (FR) | 2003-12-17 | — | — | EP | claimed |
| EP-1103554-B1 | Derivatives of dihydrofuro-(3,4-b)-quinolein-1-ones, process of préparation and phamaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-12 | — | — | EP | claimed |