Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL7011649 | 0.78 | HPGD (0.36) | LMNAALDH1A1 | |
| SCHEMBL154878 | 0.74 | — | — | |
| Ethylene Glycol SCHEMBL5517669 | 0.74 | KMT2A (0.40) | LMNAALDH1A1 | |
| Benzaldehyde SCHEMBL4954589 | 0.73 | ALDH1A1 (0.47) | LMNAALDH1A1 | |
| Ethylene Glycol SCHEMBL6809630 | 0.71 | HSD17B10 (0.50) | LMNAALDH1A1 | |
| Ethylene SCHEMBL9455100 | 0.70 | LMNA (0.36) | LMNA | |
| Ethylene Glycol SCHEMBL10901315 | 0.69 | CYP4F2 (0.37) | LMNAALDH1A1 | |
| Ethylene Glycol SCHEMBL11190297 | 0.69 | FGFR4 (0.32) | ALDH1A1 | |
| SCHEMBL569625 | 0.69 | LMNA (0.43) | LMNAALDH1A1 | |
| Ethylene Glycol SCHEMBL5513820 | 0.69 | TYR (0.40) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690863-B1 | TETRACYCLIC COMPOUNDS AS DOPAMINE AGONISTS | ABBOTT LAB (US) | 2003-03-05 | — | — | EP | disclosed |
| US-5597832-A | TREATMENT OF NEUROLOGICAL, PSYCHOLOGICAL, CARDIOVASCULAR DISORDERS, AND SUBSTANCE ABUSE, BEHAVIOR DISORDERS, COGNITIVE IMPAIRMENT AND ATTENTION DEFICIT DISORDER | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0690863-A1 | TETRACYCLIC COMPOUNDS AS DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0690863-A4 | TETRACYCLIC COMPOUNDS AS DOPAMINE AGONISTS | ABBOTT LAB (US) | 1995-11-07 | — | — | EP | disclosed |
| WO-1994022858-A1 | TETRACYCLIC COMPOUNDS AS DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1994-10-13 | — | — | WO | disclosed |