Ethylene Glycol

Ethylene Glycol

SCHEMBL6809630

CCOC(C)OCC.O=Cc1ccc(Cl)cc1.OCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.50
TYR P14679 1/20 0.42
TACR2 P21452 1/20 0.42
ALDH1A1 P00352 6/20 0.39
ALDH1A3 P47895 2/20 0.39
HPGD P15428 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.38
MAOB P27338 1/20 0.37
PTGER4 P35408 1/20 0.36
ALDH3A1 P30838 1/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
PTGS2 P35354 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C1 Q04828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10763720 0.94 HSD17B10 (0.57) HSD17B10TYRTACR2ALDH1A1ALDH1A3
Benzaldehyde SCHEMBL4954589 0.84 ALDH1A1 (0.47) TYRALDH1A1ALDH1A3L3MBTL1LMNA
Ethylene Glycol SCHEMBL5513820 0.82 TYR (0.40) TYRALDH1A1ALDH1A3HPGDTDP1
Ethylene Glycol SCHEMBL5517669 0.82 KMT2A (0.40) TYRALDH1A1ALDH1A3HPGDL3MBTL1
Ethylene SCHEMBL6226363 0.81 LMNA (0.48) HSD17B10TYRALDH1A1ALDH1A3HPGD
4-Hydroxybenzaldehyde SCHEMBL17941268 0.80 ALDH5A1 (0.57) TYRALDH1A1ALDH1A3LMNAMAOB
Cyclopropane SCHEMBL6228970 0.80 LMNA (0.46) TYRALDH1A1ALDH1A3HPGDLMNA
Ethylene Glycol SCHEMBL10901315 0.80 CYP4F2 (0.37) TYRTACR2ALDH1A1ALDH1A3HPGD
Alcohol SCHEMBL27886084 0.79 HSD17B10 (0.73) HSD17B10TYRTACR2ALDH1A1ALDH1A3
SCHEMBL10736418 0.78 CYP2A6 (0.59) HSD17B10TYRALDH1A1ALDH1A3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6833470-B2 Reaction of protected chlorobenzaldehydes with lithium in an inert solvent and reacting lithiated product with a trihalo-, trialkoxy-, trialkylthio- or tris(dialkylamino)- borane CLARIANT GMBH (DE) 2004-12-21 US disclosed
US-20040049050-A1 Method for producing formylphenylboronic acids EUTICALS GMBH (DE) 2004-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040049050-A1 Method for producing formylphenylboronic acids MAOB, BLVRB, FOSB HSD17B10 729/4885TYR 65/4885TACR2 2805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.