Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | METAP1 | P53582 | 4/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093012 | 0.82 | SMN1; SMN2 (0.49) | ACHEACP3SMN1; SMN2KDM4EMAPT | |
| SCHEMBL388171 | 0.72 | ACHE (0.59) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7998826 | 0.72 | ACHE (0.59) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL1093558 | 0.72 | ACHE (0.59) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL32679178 | 0.72 | ACHE (0.59) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30737574 | 0.72 | ACHE (0.59) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL32679177 | 0.72 | ACHE (0.59) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14157895 | 0.71 | ACHE (0.63) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5539639 | 0.71 | ACHE (0.63) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11818087 | 0.70 | ACHE (0.61) | ACHEMETAP1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841739-B1 | PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL] PIPERIDINE OR SALT THEREOF VIA NOVEL INTERMEDIATE | JUBILANT ORGANOSYS LTD (IN) | 2013-02-20 | — | — | EP | disclosed |
| US-8124783-B2 | Process for producing 1-benzyl-4-[5,6-dimethoxy-1-indanon-2-yl)methyl] piperidine or its salt thereof via novel intermediate | JUBILANT ORGANOSYS LIMITED (IN) | 2012-02-28 | — | — | US | disclosed |
| US-20090137812-A1 | PROCESS FOR PRODUCING 1-BENZYL-4-[5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE | JUBILANT ORGANOSYS LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| EP-1841739-A4 | PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE | JUBILANT ORGANOSYS LTD (IN) | 2008-10-01 | — | — | EP | disclosed |
| EP-1841739-A1 | PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE | Jubilant Organosys Limited (IN) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006070396-A1 | PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE | JUBILANT ORGANOSYS LIMITED (IN) | 2006-07-06 | — | — | WO | disclosed |
| WO-2005076749-A2 | A NOVEL PROCESS FOR THE PREPARATION OF 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE | JUBILANT ORGANOSYS LIMITED (IN) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137812-A1 | PROCESS FOR PRODUCING 1-BENZYL-4-[5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE | TET2, DHPS, AZI2 | ACHE 2994/4885METAP1 925/4885ACP3 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.