Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009704 | 0.99 | PPARG (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL7011920 | 0.98 | PPARG (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL7006585 | 0.94 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL7010808 | 0.92 | AGTR1 (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL7011915 | 0.91 | AGTR1 (0.45) | PPARGAGTR1AGTR2 | |
| SCHEMBL7015976 | 0.88 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8332201 | 0.82 | AGTR1 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL61 | 0.82 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9031719 | 0.82 | PPARG (0.48) | PPARGAGTR1AGTR2 | |
| SCHEMBL7304283 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| EP-0518033-A1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |