Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013002 | 0.82 | JAK3 (0.36) | AOC3LMNASMN1; SMN2JAK2JAK3 | |
| SCHEMBL7012017 | 0.78 | SLC6A9 (0.35) | SLC6A9SLC6A5ALDH1A1METJAK2 | |
| SCHEMBL7012012 | 0.78 | SLC6A9 (0.35) | SLC6A9SLC6A5ALDH1A1METJAK2 | |
| SCHEMBL7020495 | 0.71 | KCNH2 (0.39) | ALDH1A1LMNASMN1; SMN2KMT2AKCNH2 | |
| SCHEMBL7020395 | 0.69 | NPY1R (0.34) | SLC6A9SLC6A5ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7016427 | 0.69 | CFTR (0.40) | ALDH1A1L3MBTL1LMNASMN1; SMN2KMT2A | |
| SCHEMBL2377249 | 0.69 | HTR7 (0.48) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL6679985 | 0.68 | CYP2D6 (0.51) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL7012953 | 0.68 | AOC3 (0.36) | AOC3 | |
| SCHEMBL30270586 | 0.67 | CYP1A2 (0.52) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |