Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018655 | 0.89 | AOC3 (0.36) | KMT2A | |
| SCHEMBL7012012 | 0.88 | SLC6A9 (0.35) | SLC6A9SLC6A5JAK2JAK3PTK2 | |
| SCHEMBL7013004 | 0.82 | AKT1 (0.36) | JAK2JAK3METNPC1RAB9A | |
| SCHEMBL7012014 | 0.78 | SLC6A9 (0.37) | SLC6A9SLC6A5JAK2JAK3PTK2 | |
| SCHEMBL7018651 | 0.77 | AOC3 (0.35) | — | |
| SCHEMBL7012953 | 0.72 | AOC3 (0.36) | — | |
| SCHEMBL7012999 | 0.71 | JAK3 (0.35) | JAK2JAK3MET | |
| SCHEMBL7020498 | 0.71 | KCNH2 (0.41) | KMT2ANPC1KCNH2RAB9A | |
| SCHEMBL7020395 | 0.69 | NPY1R (0.34) | SLC6A9SLC6A5KMT2ANPC1KCNH2 | |
| SCHEMBL7016255 | 0.69 | ALDH1A1 (0.34) | SLC6A9SLC6A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |