Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | MATK | P42679 | 1/20 | 0.33 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799643 | 0.82 | KMT2A (0.47) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| Esafloxacin SCHEMBL1344407 | 0.73 | LMNA (0.69) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| Esafloxacin SCHEMBL1231132 | 0.72 | LMNA (0.68) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL6802360 | 0.71 | CKS1B (0.41) | KMT2ADPP4PIM3PIM1 | |
| SCHEMBL7011369 | 0.71 | PRKD3 (0.43) | KMT2ADPP4DPP7DYRK1APIM3 | |
| SCHEMBL9824429 | 0.69 | KMT2A (0.45) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9824535 | 0.69 | KMT2A (0.45) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL7015648 | 0.69 | PIM1 (0.40) | DYRK1APIM3PRKD3PIM1GSK3A | |
| SCHEMBL4515894 | 0.68 | KMT2A (0.48) | KMT2AHRH4DPP4DYRK1APIM3 | |
| SCHEMBL4515898 | 0.68 | KMT2A (0.48) | KMT2AHRH4DPP4DYRK1APIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028950-B1 | 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2003-05-02 | — | — | EP | claimed |