Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008921 | 0.82 | PKM (0.43) | TSHRPKMNPSR1RXFP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9275506 | 0.82 | TSHR (0.43) | TSHRPKMNPSR1RXFP1ALDH1A1 | |
| SCHEMBL7011260 | 0.81 | NPSR1 (0.40) | TSHRPKMNPSR1RXFP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6867811 | 0.81 | PKM (0.43) | TSHRPKMNPSR1RXFP1ALDH1A1 | |
| SCHEMBL7007914 | 0.78 | GRM2 (0.37) | TSHRPKMALDH1A1LMNAKDM4E | |
| SCHEMBL7007419 | 0.75 | GRM2 (0.33) | TSHRPKM | |
| SCHEMBL8008219 | 0.75 | RAB9A (0.56) | NPSR1ALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL8008533 | 0.75 | ALDH1A1 (0.53) | TSHRPKMNPSR1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8308547 | 0.74 | RAB9A (0.55) | NPSR1ALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL8008406 | 0.74 | LMNA (0.38) | TSHRPKMALDH1A1KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772593-B1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6162809-A | Pyridylthio compounds for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-19 | — | — | US | disclosed |
| WO-1996002505-A1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |