Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121832 | 0.98 | USP2 (0.47) | USP2SMN1; SMN2ALOX15LMNAGRIN2D | |
| SCHEMBL8120963 | 0.97 | USP2 (0.44) | USP2SMN1; SMN2ALOX15LMNAGRIN2D | |
| SCHEMBL7265243 | 0.69 | ALDH1A1 (0.49) | SMN1; SMN2LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8123253 | 0.69 | USP2 (0.67) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL20681024 | 0.66 | GRIN2D (0.37) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8124714 | 0.65 | USP2 (1.00) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL6096035 | 0.65 | GRIN2D (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6701780 | 0.64 | ACHE (0.40) | USP2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8113838 | 0.64 | USP2 (0.97) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL7348559 | 0.63 | SMN1; SMN2 (0.52) | USP2SMN1; SMN2ALOX15LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579359-B2 | 1-alkoxy 1H-imidazo ring systems and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-08-25 | — | — | US | disclosed |
| US-20090005376-A1 | imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines; immunomodulators for inducing cytokine biosynthesis; for treatment of viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-01 | — | — | US | disclosed |
| US-7163947-B2 | 1-Amino 1H-imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-16 | — | — | US | disclosed |
| EP-0912564-B1 | PROCESS FOR PREPARING TETRAHYDROIMIDAZOQUINOLINAMINES | MINNESOTA MINING & MFG (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-0708773-B1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING & MFG (US) | 2000-10-04 | — | — | EP | disclosed |
| US-5886006-A | VIRICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| US-5693811-A | Process for preparing tetrahdroimidazoquinolinamines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5648516-A | INTERFERON BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5627281-A | CHEMCAL INTERMEDIATES FOR VIRICIDES BY INDUCING SYNTHESIS OF INTERFERONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0708773-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5444065-A | Viricides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1995002598-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5352784-A | Viricides; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-4031099-A | ANTIALLERGENS | BEECHAM GROUP LIMITED (EN) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005376-A1 | imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines; immunomodulators for inducing cytokine biosynthesis; for treatment of viral and neoplastic diseases | IL2, IL4, IRF3 | USP2 4037/4885SMN1; SMN2 3877/4885ALOX15 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.