Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149603 | 0.91 | ALOX5 (0.43) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7020424 | 0.85 | ALOX5 (0.46) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7011748 | 0.85 | ALOX5 (0.46) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7010787 | 0.81 | ALOX5 (0.56) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7014803 | 0.77 | KIF11 (0.52) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7013585 | 0.74 | KDM4E (0.42) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7018451 | 0.74 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9233948 | 0.72 | PIM1 (0.51) | PRKD3PIM1DYRK1APIM3GSK3A | |
| SCHEMBL9234814 | 0.72 | PIM1 (0.56) | PRKD3PIM1DYRK1APIM3GSK3A | |
| SCHEMBL7015629 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313708-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018345-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |