Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016620 | 0.90 | KIF11 (0.42) | KIF11ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7013585 | 0.86 | KDM4E (0.42) | KIF11ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7011748 | 0.82 | ALOX5 (0.46) | KIF11ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7020424 | 0.81 | ALOX5 (0.46) | KIF11ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7013967 | 0.77 | PRKD3 (0.42) | KIF11ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7149603 | 0.76 | ALOX5 (0.43) | KIF11ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7009049 | 0.76 | ALDH1A1 (0.42) | KIF11ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7015629 | 0.75 | KDM4E (0.41) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7010787 | 0.73 | ALOX5 (0.56) | ALDH1A1KDM4EHPGDMEN1LMNA | |
| SCHEMBL11208613 | 0.72 | GAA (0.47) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313708-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018345-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |