Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011748 | 0.91 | ALOX5 (0.46) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7149603 | 0.86 | ALOX5 (0.43) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7013967 | 0.85 | PRKD3 (0.42) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7010787 | 0.84 | ALOX5 (0.56) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7014803 | 0.81 | KIF11 (0.52) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7013585 | 0.77 | KDM4E (0.42) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7018451 | 0.77 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7015629 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL3474228 | 0.74 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10404697 | 0.73 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313708-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018345-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |