Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.70 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | UBE2N | P61088 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20561163 | 0.92 | ABCC8 (0.81) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL7017901 | 0.88 | LMNA (0.67) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL7018070 | 0.87 | LMNA (0.68) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL7011204 | 0.87 | LMNA (0.68) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL7011108 | 0.87 | LMNA (0.84) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| Hydrochloric Acid SCHEMBL7019827 | 0.86 | LMNA (0.82) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL7011398 | 0.86 | LMNA (0.67) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL7016279 | 0.84 | RXFP1 (0.65) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL29256880 | 0.83 | ADORA2B (0.74) | ABCC8KCNJ11LMNAMAPK1ADORA2B | |
| SCHEMBL7016345 | 0.83 | LMNA (0.66) | ABCC8KCNJ11LMNAMAPK1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |