Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 3/20 | 0.46 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277167 | 0.81 | PARG (0.56) | KMT2AMEN1KDM4EATMSMN1; SMN2 | |
| SCHEMBL7017060 | 0.81 | CASR (0.42) | TDO2IDO2CASRC1RKDM4E | |
| SCHEMBL22509709 | 0.75 | KDM4E (0.63) | KMT2AKDM4ESMN1; SMN2POLB | |
| SCHEMBL7602321 | 0.75 | POLB (0.57) | KDM4ESMN1; SMN2POLB | |
| SCHEMBL30669482 | 0.74 | POLB (0.48) | KMT2AMEN1TDO2IDO2CASR | |
| SCHEMBL9101181 | 0.74 | TDO2 (0.74) | KMT2AMEN1TDO2IDO2IDO1 | |
| SCHEMBL30669485 | 0.73 | ALDH1A1 (0.52) | KMT2AMEN1KDM4EATMSMN1; SMN2 | |
| SCHEMBL22720142 | 0.73 | KDM4E (0.57) | KMT2AMEN1TDO2IDO2KDM4E | |
| SCHEMBL7012552 | 0.73 | TUBB4A (0.52) | KDM4ESMN1; SMN2 | |
| SCHEMBL11098025 | 0.72 | ALDH1A1 (0.53) | KMT2AMEN1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-5389641-A | Fused heterocyclic compounds, having angiotensin II antagonistic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0518033-A1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |