Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277167 | 0.80 | PARG (0.56) | SMN1; SMN2ALDH1A1KDM4EKMT2APARG | |
| SCHEMBL2734535 | 0.79 | PDE10A (0.46) | POLBALDH1A1KMT2AMEN1GAA | |
| SCHEMBL30690334 | 0.77 | EGFR (0.37) | — | |
| SCHEMBL26042227 | 0.76 | DHODH (0.37) | CASRKDM4ETDP1HTTHSD17B10 | |
| SCHEMBL7602321 | 0.76 | POLB (0.57) | POLBSMN1; SMN2ALDH1A1KDM4EELANE | |
| SCHEMBL30690320 | 0.75 | DHODH (0.42) | — | |
| SCHEMBL30669485 | 0.74 | ALDH1A1 (0.52) | POLBSMN1; SMN2ALDH1A1KDM4EELANE | |
| SCHEMBL7014395 | 0.74 | KMT2A (0.46) | POLBCASRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29139165 | 0.74 | AKT1 (0.35) | — | |
| SCHEMBL30690342 | 0.74 | AKT1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008122-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 海创药业股份有限公司 | 2024-01-11 | — | — | WO | disclosed |