Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651689 | 0.89 | SMN1; SMN2 (0.73) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL9318785 | 0.89 | SMN1; SMN2 (0.73) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL7015587 | 0.86 | SMN1; SMN2 (0.57) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL7017250 | 0.83 | SMN1; SMN2 (0.55) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL13947536 | 0.83 | ALDH1A1 (0.73) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL7021535 | 0.81 | GPR139 (0.65) | GPR139SMN1; SMN2MMP9MMP8 | |
| SCHEMBL7010951 | 0.80 | MMP9 (0.50) | GPR139MMP9MMP8MEN1KMT2A | |
| SCHEMBL5968858 | 0.79 | ALDH1A1 (0.77) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL751213 | 0.79 | ALDH1A1 (0.77) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL1101522 | 0.79 | ALDH1A1 (0.77) | GPR139SMN1; SMN2LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670447-B2 | An 3-acyl-4-substituted-oxazolidin-2,5-dione that readily reacts with nucleophilic reagents such as free amino acids; use in peptide synthesis for example | MITSUI CHEMICALS, INC. (JP) | 2003-12-30 | — | — | US | disclosed |
| EP-1298127-A1 | AMINO ACID-N-CARBOXY ANHYDRIDES HVAING SUBSTITUENT AT NITROGEN | Mitsui Chemicals, Inc. (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20020173664-A1 | Amino acid-n-carboxy anhydrides hvaing substituent at nitrogen | MITSUI CHEMICALS, INC. (JP) | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173664-A1 | Amino acid-n-carboxy anhydrides hvaing substituent at nitrogen | DNPEP, HDGF, ANPEP | GPR139 797/4885SMN1; SMN2 3873/4885LMNA 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.