Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016280 | 0.90 | PIK3CD (0.43) | PIK3CDPIK3CBHDAC3HDAC1HDAC2 | |
| SCHEMBL7018034 | 0.89 | HPGD (0.42) | PIK3CDPIK3CBHDAC3HDAC1HDAC2 | |
| SCHEMBL7017560 | 0.87 | ALDH1A1 (0.36) | PIK3CDPIK3CAPIK3CBHTR2AHDAC3 | |
| SCHEMBL7012970 | 0.71 | PLA2G7 (0.48) | HTR2AMAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL7015959 | 0.69 | TP53 (0.44) | PIK3CDPIK3CAPIK3CBHDAC3HDAC1 | |
| SCHEMBL7015350 | 0.67 | TP53 (0.44) | PIK3CDPIK3CBHDAC3HDAC1HDAC2 | |
| SCHEMBL7016720 | 0.67 | SRD5A2 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7010932 | 0.67 | CYP19A1 (0.42) | PIK3CDPIK3CBHDAC3HDAC1HDAC2 | |
| SCHEMBL7016621 | 0.67 | TP53 (0.42) | PIK3CDPIK3CBHDAC3HDAC1HDAC2 | |
| SCHEMBL7139789 | 0.66 | KDM4E (0.43) | MAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |