Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016280 | 0.99 | PIK3CD (0.43) | HPGDHSD17B10ALDH1A1KDM4EPIK3CD | |
| SCHEMBL7015344 | 0.89 | PIK3CD (0.43) | HPGDHSD17B10ALDH1A1KDM4EPIK3CD | |
| SCHEMBL7017560 | 0.85 | ALDH1A1 (0.36) | HPGDHSD17B10ALDH1A1KDM4EPIK3CD | |
| SCHEMBL7015959 | 0.78 | TP53 (0.44) | ALDH1A1PIK3CDPIK3CBTP53HDAC3 | |
| SCHEMBL7015350 | 0.76 | TP53 (0.44) | PIK3CDPIK3CBTP53HDAC3HDAC1 | |
| SCHEMBL7016621 | 0.76 | TP53 (0.42) | ALDH1A1PIK3CDPIK3CBPKMTP53 | |
| SCHEMBL7014282 | 0.75 | TP53 (0.41) | PIK3CDPIK3CBTP53HDAC3HDAC1 | |
| SCHEMBL7016868 | 0.74 | ENPP2 (0.42) | HSD17B10ALDH1A1KDM4EPIK3CDPIK3CB | |
| SCHEMBL7016044 | 0.74 | PIK3CD (0.55) | KDM4EPIK3CDPIK3CBTP53HDAC3 | |
| SCHEMBL7018099 | 0.73 | LMNA (0.50) | HPGDALDH1A1KDM4ETP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |