Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021890 | 0.79 | CYP2C19 (0.33) | LMNAHSD17B10 | |
| SCHEMBL14991075 | 0.77 | ALDH1A1 (0.46) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL4444271 | 0.75 | LMNA (0.34) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL6790182 | 0.75 | ALDH1A1 (0.48) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL4444268 | 0.75 | LMNA (0.34) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL6789266 | 0.73 | NAAA (0.40) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL6721894 | 0.73 | SERPINE1 (0.33) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL6790179 | 0.73 | SERPINE1 (0.33) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL13686650 | 0.73 | PRKCA (0.39) | SERPINE1LMNAHSD17B10 | |
| SCHEMBL222663 | 0.73 | SERPINE1 (0.33) | SERPINE1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |