Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015781 | 0.87 | KMT2A (0.45) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7017592 | 0.86 | KMT2A (0.44) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL7016720 | 0.83 | SRD5A2 (0.42) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL7010932 | 0.81 | CYP19A1 (0.42) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL7015350 | 0.81 | TP53 (0.44) | KMT2APOLBTHRBTP53RAB9A | |
| Hydrochloric Acid SCHEMBL7021475 | 0.80 | L3MBTL3 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7016860 | 0.78 | KDM4E (0.43) | SMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL7011674 | 0.77 | RAB9A (0.39) | MEN1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL7016868 | 0.73 | ENPP2 (0.42) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL27629593 | 0.73 | KMT2A (0.71) | MEN1KMT2APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |