Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | UBE2N | P61088 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015993 | 0.91 | LMNA (0.66) | MAPK1LMNABRD4BRD2BRD3 | |
| SCHEMBL7018390 | 0.84 | LMNA (0.69) | MAPK1LMNASMN1; SMN2HTTUBE2N | |
| SCHEMBL7013136 | 0.84 | LMNA (0.65) | MAPK1LMNASMN1; SMN2HTTUBE2N | |
| SCHEMBL8643969 | 0.82 | SMN1; SMN2 (0.44) | MAPK1LMNABRD4BRD2BRD3 | |
| SCHEMBL7015175 | 0.82 | LMNA (0.62) | MAPK1LMNASMN1; SMN2TSHRHTT | |
| SCHEMBL7011108 | 0.82 | LMNA (0.84) | MAPK1LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7012058 | 0.82 | LMNA (0.65) | MAPK1LMNASMN1; SMN2HTTUBE2N | |
| Hydrochloric Acid SCHEMBL7019827 | 0.81 | LMNA (0.82) | MAPK1LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL555093 | 0.81 | ALDH1A1 (0.65) | MAPK1LMNAALDH1A1BRD4KMT2A | |
| SCHEMBL7015123 | 0.78 | LMNA (0.66) | MAPK1LMNAKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |