Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016050 | 1.00 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1KDM4ECYP2C19 | |
| Hydrochloric Acid SCHEMBL5941225 | 0.94 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1KDM4ECYP2C19 | |
| SCHEMBL6656271 | 0.87 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB | |
| SCHEMBL4758549 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EFFAR1 | |
| SCHEMBL4758546 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EFFAR1 | |
| SCHEMBL8911799 | 0.84 | LTA4H (0.49) | ALDH1A1SMN1; SMN2MAPK1KDM4ECYP2C19 | |
| SCHEMBL7026294 | 0.84 | LTA4H (0.49) | ALDH1A1SMN1; SMN2MAPK1KDM4ECYP2C19 | |
| Trifluoroacetic Acid SCHEMBL6654304 | 0.80 | SPHK1 (0.43) | ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB | |
| SCHEMBL9298867 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KDM4ECYP2C19L3MBTL1 | |
| SCHEMBL23746785 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307978-B | Inorganic microsphere modified by cyclodextrin grafted chiral proline metal complex and preparation method and application thereof | 昆明理工大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-113307978-A | Inorganic microsphere modified by cyclodextrin grafted chiral proline metal complex and preparation method and application thereof | 昆明理工大学 | 2021-08-27 | — | — | CN | disclosed |
| EP-0574174-B1 | Angiotensin II antagonists | LILLY CO ELI (US) | 2003-08-13 | — | — | EP | disclosed |
| CN-1045768-C | Angiotension II antagonists | LILLY CO ELI (US) | 1999-10-20 | — | — | CN | disclosed |
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5612360-A | AROMATIC N-HETEROCYCLIC COMPOUNDS AS HYPOTENSIVE AGENTS WITH ACID GROUPS, SULFONYLCARBOXAMIDES OR TETRAZOLE GROUPS | ELI LILLY AND COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| US-5569768-A | USEFUL IN TREATING HYPERTENSION, CONGESTIVE HEART FAILURE, GLAUCOMA AND RENAL INSUFFICIENCY | ELI LILLY AND COMPANY (US) | 1996-10-29 | — | — | US | disclosed |
| US-5556981-A | Angiotensin II antagonist intermediates | ELI LILLY AND COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| US-5484780-A | CARDIOVASCULAR, HYPOTENSIVE | ELI LILLY AND COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-5401851-A | Preparation of proline derivatives | ELI LILLY AND COMPANY (US) | 1995-03-28 | — | — | US | disclosed |
| CN-1085897-A | Angiotension II antagonists | LILLY CO ELI (US) | 1994-04-27 | — | — | CN | disclosed |
| EP-0574174-A2 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| EP-0573271-A1 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |