Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026294 | 1.00 | LTA4H (0.49) | LTA4HALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL3540725 | 0.91 | LTA4H (0.47) | LTA4HALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL7016053 | 0.84 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1HTTCYP2C19 | |
| SCHEMBL7016050 | 0.84 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1HTTCYP2C19 | |
| Hydrochloric Acid SCHEMBL3545106 | 0.84 | L3MBTL1 (0.46) | LTA4HNPC1RAB9A | |
| SCHEMBL6656271 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1HTTKDM4E | |
| SCHEMBL25967749 | 0.80 | KMT2A (0.50) | LTA4HKMT2AFKBP1AALOX5TSHR | |
| SCHEMBL30675399 | 0.79 | POLB (0.47) | LTA4HALDH1A1SMN1; SMN2KMT2AFKBP1A | |
| Hydrochloric Acid SCHEMBL5941225 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KMT2AMAPK1HTT | |
| SCHEMBL20253879 | 0.76 | KMT2A (0.46) | LTA4HKMT2AFKBP1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612360-A | AROMATIC N-HETEROCYCLIC COMPOUNDS AS HYPOTENSIVE AGENTS WITH ACID GROUPS, SULFONYLCARBOXAMIDES OR TETRAZOLE GROUPS | ELI LILLY AND COMPANY (US) | 1997-03-18 | — | — | US | disclosed |