Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758546 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2FFAR1HRH3SLC6A9 | |
| SCHEMBL7016050 | 0.85 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2FFAR1KDM4E | |
| SCHEMBL7016053 | 0.85 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2FFAR1KDM4E | |
| Hydrochloric Acid SCHEMBL5941225 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6656271 | 0.74 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7026294 | 0.71 | LTA4H (0.49) | ALDH1A1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL8911799 | 0.71 | LTA4H (0.49) | ALDH1A1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL4338040 | 0.71 | SLC6A9 (0.68) | ALDH1A1HRH3SLC6A9KDM4ETP53 | |
| SCHEMBL4338045 | 0.71 | SLC6A9 (0.68) | ALDH1A1HRH3SLC6A9KDM4ETP53 | |
| SCHEMBL2030130 | 0.71 | NPBWR1 (0.53) | SLC6A9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004067-A2 | ALPHA-2-DELTA-1 SELECTIVE COMPOUNDS FOR DISORDERS OF THE NERVOUS SYSTEM | PFIZER PRODUCTS INC. (US) | 2008-01-10 | — | — | WO | disclosed |