Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 5/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732678 | 0.86 | P2RX3 (0.40) | PKMDHODHGPR139MAPTP2RX3 | |
| SCHEMBL6728750 | 0.85 | TDP1 (0.35) | DHODHGPR139 | |
| SCHEMBL6730676 | 0.81 | ALDH1A1 (0.36) | DHODHGPR139 | |
| SCHEMBL6724655 | 0.80 | SLC5A2 (0.36) | DHODHGPR139 | |
| SCHEMBL28752058 | 0.79 | SLC5A2 (0.37) | PKMMDM2MIFGPR139TBXA2R | |
| SCHEMBL6727520 | 0.76 | GPR139 (0.38) | DHODHGPR139 | |
| SCHEMBL6727367 | 0.75 | PPOX (0.43) | PKMDHODHMAPTATM | |
| SCHEMBL28749850 | 0.74 | SLC5A1 (0.34) | DHODHGPR139 | |
| SCHEMBL4163257 | 0.74 | PPOX (0.45) | — | |
| SCHEMBL6724485 | 0.71 | GPR139 (0.34) | GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333031-A1 | BICYCLIC TRIAZOLONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |